Anti-LY6C1 Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: RB6-8C5]

Supplier: Tonbo Biosciences

C57Bl/6 bone marrow cells were stained with 0.06 ug PE Anti-Mouse Ly-6G (50-5931) (solid line) or 0.06 ug PE Rat IgG2b isotype control (dashed line).

C57Bl/6 bone marrow cells were stained with 0.06 ug PE Anti-Mouse Ly-6G (50-5931) (solid line) or 0.06 ug PE Rat IgG2b isotype control (dashed line).

50-5931-U025 50-5931-U100

10051-366EA 53.72 CAD

10051-366 10051-368

Anti-LY6C1 Rat Monoclonal Antibody (PE (Phycoerythrin)) [clone: RB6-8C5]

Antibodies

The RB6-8C5 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.

The RB6-8C5 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: The RB6-8C5 antibody has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C. Other reports suggest that this antibody is specific for Ly-6G, without cross-reactivity for Ly-6C (Nagendra S. and Schlueter AJ. 2003. Cytometry A, 58(2): 195-200.

Type: Primary
Antigen: LY6C1
Clonality: Monoclonal
Clone: RB6-8C5
Conjugation: PE (Phycoerythrin)
Epitope:
Host: Rat
Isotype: IgG2b
Reactivity: Mouse

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