Anti-LY6C1 Rat Antibody (redFluor® 710) [clone: RB6-8C5]

Supplier: Tonbo Biosciences

C57Bl/6 bone marrow cells were stained with 0.015 ug redFluor™ 710 Anti-Mouse Ly-6G (80-5931) (right panel) or 0.015 ug redFluor™ 710 Rat IgG2b isotype control (left panel).

C57Bl/6 bone marrow cells were stained with 0.015 ug redFluor™ 710 Anti-Mouse Ly-6G (80-5931) (right panel) or 0.015 ug redFluor™ 710 Rat IgG2b isotype control (left panel).

80-5931-U025 80-5931-U100

10141-122EA 94.8 CAD

10141-122 10141-124

Anti-LY6C1 Rat Antibody (redFluor® 710) [clone: RB6-8C5]

Antibodies

The RB6-8C5 antibody binds to mouse Ly-6G, commonly known as Gr-1, a member of the Ly-6 superfamily of GPI-anchored cell surface proteins with roles in cell signaling and cell adhesion. Gr-1 is differentially expressed during development and maturation of cells in the myeloid lineage and is expression at varying stages and levels on monocytes, macrophages, granulocytes, and peripheral neutrophils.

The RB6-8C5 antibody is typically used in combination with the macrophage labeling antibody M1/70 (Anti-CD11b) for phenotypic analysis of monocytes, macrophages and granulocytes. Note: The RB6-8C5 antibody has been reported to cross-react with Ly-6C on cells expressing this antigen (Fleming et al. 1993. J. Immunol. 151:2399-2408 and Sasmono et al. 2007. J. Leukoc. Biol. 82: 111-123) and has been cited in the literature for identification of Ly-6G/Ly-6C. Other reports suggest that this antibody is specific for Ly-6G, without cross-reactivity for Ly-6C (Nagendra S. and Schlueter AJ. 2003. Cytometry A, 58(2): 195-200.

Type: Primary
Antigen: LY6C1
Clonality:
Clone: RB6-8C5
Conjugation: redFluor® 710
Epitope:
Host: Rat
Isotype: IgG2b
Reactivity: Mouse

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