Anti-PTPRC Mouse Monoclonal Antibody (violetFluor® 450) [clone: HI100]

Supplier: Tonbo Biosciences

Human peripheral blood lymphocytes were stained with 5 uL (0.5 ug) violetFluor™ 450 Anti-Human CD45RA (75-0458) (solid line) or 0.5 ug violetFluor™ 450 Mouse IgG2b isotype control (dashed line).

Human peripheral blood lymphocytes were stained with 5 uL (0.5 ug) violetFluor™ 450 Anti-Human CD45RA (75-0458) (solid line) or 0.5 ug violetFluor™ 450 Mouse IgG2b isotype control (dashed line).

75-0458-T025 75-0458-T100

10050-550EA 143.78 CAD

10050-550 10051-822

Anti-PTPRC Mouse Monoclonal Antibody (violetFluor® 450) [clone: HI100]

Antibodies

The HI100 antibody reacts with the human CD45 isoform known as CD45RA, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RB and CD45RO.

The HI100 antibody is widely used as a marker for human CD45RA expression on naïve and activated T cells, B cells, and monocytes.

Type: Primary
Antigen: PTPRC
Clonality: Monoclonal
Clone: HI100
Conjugation: violetFluor® 450
Epitope:
Host: Mouse
Isotype: IgG2b
Reactivity: Human, Chimpanzee

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