Anti-KLRB1 Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: HP-3G10]

Supplier: Tonbo Biosciences

Human peripheral blood lymphocytes were stained with 5 uL (0.25 ug) APC Anti-Human CD161 (20-1619) (solid line) or 0.25 ug APC Mouse IgG1 isotype control (dashed line).

Human peripheral blood lymphocytes were stained with 5 uL (0.25 ug) APC Anti-Human CD161 (20-1619) (solid line) or 0.25 ug APC Mouse IgG1 isotype control (dashed line).

20-1619-T025 20-1619-T100

10050-594EA 137.46 CAD

10050-594 10050-596

Anti-KLRB1 Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: HP-3G10]

Antibodies

The HP-3G10 antibody is specific for human CD161, also known as NKR-P1A, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. CD161 exists as a homodimer which is prominently expressed on natural killer (NK) and NKT cells, where it is proposed to regulate the function of both cell types. CD161 is also found on T cell subsets, including T regulatory cells (Tregs), memory/effector CD4+ T cells, and CD8+ T cells. Th17 cells have been demonstrated to co-express CD161, as surface IL-17A+ cells are contained within the CD161+ fraction of CD4 T cells, so that CD161 (in combination with CCR6) is often used as a marker for enrichment of Th17 cells.

The HP-3G10 antibody may be used for flow cytometric analysis of CD161 on NK and NKT cells, as well as on various T cell subsets. The antibody is also reported to be cross-reactive with Baboon, Chimpanzee and Rhesus CD161.

Type: Primary
Antigen: KLRB1
Clonality: Monoclonal
Clone: HP-3G10
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Chimpanzee, Baboon, Rhesus

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