Anti-FOXP3 Rat Antibody (PE (Phycoerythrin)) [clone: MF23]

Supplier: Tonbo Biosciences

C57Bl/6 splenocytes were stained with APC Anti-Mouse CD4 (20-0042), followed by intracellular staining with 0.25 ug PE Anti-Mouse Foxp3 (50-0191) (right panel) or 0.25 ug PE Rat IgG2b isotype control (left panel).

C57Bl/6 splenocytes were stained with APC Anti-Mouse CD4 (20-0042), followed by intracellular staining with 0.25 ug PE Anti-Mouse Foxp3 (50-0191) (right panel) or 0.25 ug PE Rat IgG2b isotype control (left panel).

50-0191-U025 50-0191-U100

10141-198EA 173.8 CAD

10141-198 10141-200

Anti-FOXP3 Rat Antibody (PE (Phycoerythrin)) [clone: MF23]

Antibodies

The MF23 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is a member of the forkhead box or winged helix family of transcription factors and is expressed at constitutively high levels in Treg cells. Forced expression of Foxp3 in conventional T cells results in the upregulation of Treg associated molecules such as CD25, CTLA-4, and GITR and is sufficient to impart suppressive functional activity to these cells.

Type: Primary
Antigen: Foxp3
Clonality:
Clone: MF23
Conjugation: PE
Epitope:
Host: Rat
Isotype: IgG2b
Reactivity: Mouse

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