XRN-1
Supplier: New England Biolabs (NEB)
M0338S
M0338L
CA101449-366EA
159
CAD
CA101449-366
CA102855-158
XRN-1
Enzymes
XRN-1 is highly processive 5´→3´ exoribonuclease, requiring 5´ monophosphate
It also acts on 5´ monophosphate ssDNA with greatly reduced efficiency. XRN-1 is not efficient in removing RNAs with recessed 5´P, like tRNA. It does not cleave dsDNA, ssDNA and RNA which contain di, triphosphate, OH and capped 5´ ends.
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