E. coli Topoisomerase I

Supplier: New England Biolabs (NEB)

M0301L M0301S
CA101227-644EA 499 CAD
CA101227-644 CA101227-646
E. coli Topoisomerase I
Enzymes

Topoisomerase I (E.coli) catalyzes the relaxation of negatively supercoiled DNA.


Topoisomerase I has also been implicated in knotting and unknotting DNA and in linking complementary rings of single-stranded DNA into double-stranded rings. The intact holoenzyme is a 97 kDa protein.

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