3'-O-Me-m7G(5')ppp(5')G RNA Cap Structure Analog, New England Biolabs

Supplier: New England Biolabs (NEB)

3'-O-Me-m7G(5')ppp(5')G RNA Cap Structure Analog - 1 umol

3'-O-Me-m7G(5')ppp(5')G RNA Cap Structure Analog - 1 umol

S1411L S1411S

CA101227-246EA 1025 CAD

CA101227-246 CA101227-248

3'-O-Me-m7G(5')ppp(5')G RNA Cap Structure Analog, New England Biolabs

Nucleic Acid Reagents Nucleic Acid Modification and Labelling

Blocking of the 3´ -hydroxyl of m7G with 3´-0-Me assures that the capped transcripts are homogeneous

Reliable expression
Substantial yields (up to 100 mg/L) in more than 75% of the cases tested
Expression in either the cytoplasm or periplasm
Periplasmic expression enhances folding of proteins with disulfide bonds
Fusion to MBP has been shown to enhance the solubility of proteins expressed in E. coli
Gentle elution with maltose
No detergents or harsh denaturants

The 3´ - hydroxyl of the non-methylated G is the only 3´ - hydroxyl available for initiation.

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