Anti-RSEC6 Mouse Monoclonal Antibody

Supplier: Enzo Life Sciences
VAM-SV021-D VAM-SV021D VAM-SV021F VAM-SV021-F
CA95046-458EA 395 CAD
95046-458 CA95046-458 95046-460 CA95046-460
Anti-RSEC6 Mouse Monoclonal Antibody
Antibodies
rSec6 and rSec8 are rat homologs of the yeast Sec6 and Sec8 proteins that are essential for protein transport between the Golgi apparatus and the plasma membrane. In yeast, Sec8 is part of a 19.5S complex that includes Sec6 and Sec15, that also associate with the ras-like GTP binding protein Sec4. An analogous 17S complex in rat brain was found to contain rSec6 and rSec8, along with eight proteins with a combined molecular weight of 743 kDa. The membrane-associated rSec6/8 complex co-immunoprecipitates with syntaxin, providing evidence that this complex is involved in synaptic vesicle docking and fusion at the presynaptic terminal.

  • For Immunocytochemistry, Immunohistochemistry, Western Blot

Recognizes human, mouse, rat, bovine, dog, chicken, hamster, monkey, pig, rabbit and sheep rSec6. Detects a band of ~87kDa by Western blot.

Type: Primary
Antigen: RSEC6
Clonality: Monoclonal
Clone:
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG2a
Reactivity: Human
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