Anti-HSP70 Mouse Monoclonal Antibody [clone: C92F3A-5]

Supplier: Enzo Life Sciences
ADI-SPA-810-F SPA-810F ADI-SPA-810-D ADI-SPA-810-J SPA-810D
CA200062-686EA 399 CAD
CA200062-686 200062-688 CA200062-688 200062-686 95039-012
Anti-HSP70 Mouse Monoclonal Antibody [clone: C92F3A-5]
Antibodies
The Hsp70 family of heat shock proteins contains multiple homologs ranging in size from 66-78 kDa, and are the eukaryotic equivalents of the bacterial DnaK. The most studied Hsp70 members include the cytosolic stress-induced Hsp70 (Hsp72), the constitutive cytosolic Hsc70 (Hsp73), and the ER-localized BiP (Grp78). Hsp70 family members contain highly conserved N-terminal ATP-ase and C-terminal protein binding domains. Binding of peptide to Hsp70 is assisted by Hsp40, and stimulates the inherent ATPase activity of Hsp70, facilitating ATP hydrolysis and enhanced peptide binding. Hsp70 nucleotide exchange and substrate binding coordinates the folding of newly synthesized proteins, the re-folding of misfolded or denatured proteins, coordinates trafficking of proteins across cellular membranes, inhibits protein aggregation, and targets the degradation of proteins via the proteasomal pathway.

  • For ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot, EM

Recognizes human, mouse, rat, bovine, beluga, C. elegans, dog, chicken, Drosophila, fish, gerbil, guinea pig, hamster, monkey, pig, rabbit, sheep, teal, and Xenopus HSP70 (HSP72). Detects a band of ~70kDa by Western blot.

Type: Primary
Antigen: HSP70
Clonality: Monoclonal
Clone: C92F3A-5
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human, Mouse, Rat, Sheep, Dog, Pig, Monkey, Avian, Bovine, Beluga, C. Elegans, Chicken, Drosophila, Fish, Gerbil, Guinea Pig, Hamster, Rabbit, Teal, Xenopus
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