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Description: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation. [COFACTOR] Divalent metal cations. Manganese or cobalt.
Catalog Number: 76120-200
Supplier: Bioss


Description: Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.
Catalog Number: 76084-428
Supplier: Bioss


Description: Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.
Catalog Number: 10370-552
Supplier: Bioss


Description: A range of analytical reagents for photometric water analysis in the NANOCOLOR® standard test version.
Catalog Number: 77578-620
Supplier: Macherey-Nagel

New Product


Description: Use this test paper to detect the presence of water or to perform qualitative tests of relative humidity. Size of each sheet: 20 x 25cm. Package of 12.
Catalog Number: 470326-694
Supplier: Precision Laboratories


Description: Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.
Catalog Number: 76084-430
Supplier: Bioss


Description: Saturated with 70% IPA/30% DI water, these wipes contain four clean-cut, sealed edges to eliminate fiber contamination.
Catalog Number: 10210-949
Supplier: High-Tech Conversions


Description: Protein tags are protein or peptide sequences located either on the C- or N- terminal of the target protein, which facilitates one or several of the following characteristics: solubility, detection, purification, localization and expression. His tag is often used for affinity purification and binding assays. Expressed His-tagged proteins can be purified and detected easily because the string of histidine residues binds to several types of immobilized metal ions, including nickel, cobalt and copper, under specific buffer conditions. The His tag antibody is a useful tool for monitoring of the His-tagged proteins, and recognizes His-tags placed at N-terminal, C-terminal, and internal regions of fusion proteins expressed in bacteria, insect, and mammalian cells.
Catalog Number: 10082-264
Supplier: Proteintech


Description: High-quality tweezers feature Ergo-Tweeze® soft cushioned grips.
Catalog Number: 75880-786
Supplier: Excelta


Description: Cobaltima® tweezers offer the highest precision and the ideal material for a tool to be used with delicate parts under high magnification.
Catalog Number: 63042-114
Supplier: Excelta

Small Business Enterprise Minority or Woman-Owned Business Enterprise


Description: Series N30502XX Lumina™ 2" (50 mm) diameter multi-element lamps are designed to be used with the PinAAcle™ and AAnalyst™ Atomic Absorption spectrometer series of instruments.
Catalog Number: CA97013-302
Supplier: PerkinElmer


Description: This radiochemistry standard is provided as a convenient, easy-to-prepare concentrate
Catalog Number: CA11022-686
Supplier: ERA

SDS


Description: HIF1, the major regulator of the cellular responses to hypoxia, consists of an oxygen-sensitive subunit, HIF1alpha (HIFA), and an oxygen-insensitive subunit, HIF1beta (arylhydrocarbon receptor nuclear transporter [ARNT]). Although the mRNA is constitutively and ubiquitously expressed and transcribed, the HIF1A protein is rapidly degraded in the presence of oxygen. The half-life of HIF1A under ambient oxygeconditions is less than 5 min. Both hypoxic conditions and chemical hydroxylase inhibitors (such as desferrioxamine and cobalt) inhibit HIF-1α degradation and lead to its stabilization. In addition, HIF-1α can be induced in an oxygen-independent manner by various cytokines through the PI3K-AKT-mTOR pathway.
Catalog Number: 10088-244
Supplier: Proteintech


Description: This mounting medium is made with limonene, a natural product from orange peels. It preserves  tissues and cell smears that can be dehydrated with organic solvents in immunohistochemistry, e.g. DAB and DAB with nickel or cobalt.
Catalog Number: 100501-606
Supplier: Electron Microscopy Sciences

Minority or Woman-Owned Business Enterprise


Description: G-Biosciences' HOOK™ 6X His Protein Purification (Bacteria) is a complete kit for the purification of soluble, 6X His tagged protein from bacterial cultures
Catalog Number: CA89167-832
Supplier: G-Biosciences

SDS


Description: The Pierce™ His Protein Interaction Pull-Down Kit contains the necessary components to capture and purify proteins that interact with His-tagged fusion proteins.
Catalog Number: CAPI21277
Supplier: Thermo Scientific