Anti-PDGFRB Mouse Monoclonal Antibody [clone: 42G12]

Supplier: Enzo Life Sciences
905-682-100
CA101410-450EA 532.46 CAD
CA101410-450
Anti-PDGFRB Mouse Monoclonal Antibody [clone: 42G12]
Antibodies
Mitogenic platelet derived growth factor (PDGF) signaling is mediated by the PDGF tyrosine kinase receptors PDGFRα and PDGFRβ, which exist as homo- or heterodimer isoforms (αα, ββ, αβ). Secretion of PDGFs and expression of PDGFRs in a broad distribution of cell types contributes to regulation of cellular processes including cell growth, actin reorganization, prevention of apoptosis, and chemotaxis. Structurally, the transmembrane PDGFRs are composed of an N-terminal extracellular domain with five immunoglobulin repeats, and an intracellular domain containing two spaced tyrosine kinaseMore Product Information
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SPECIFICATIONS

Antigen symbol PDGFRB
Environmentally Preferable
Antigen name Platelet Derived Growth Factor Receptor beta
Antigen synonyms JTK12|CD140b antigen|CD140B|PDGFR1|Beta platelet-derived growth factor receptor
Antibody type Primary
Clonality Monoclonal
Clone 42G12
Reactivity Rat,Mouse
Host Mouse
Isotype IgG1
Western blot Yes
ImmunoChemistry Yes
Form Liquid. In PBS, pH 7.2, containing 0.09% sodium azide and 50% glycerol.
Purification Protein G affinity purified

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