Mouse Recombinant IL-33 (from E. coli)

Supplier: VWR International

77752-304 77752-306 77752-308 77752-310
77752-304EA 1464.15 CAD
77752-304 77752-306 77752-308 77752-310
Mouse Recombinant IL-33 (from E. coli)
Proteins and Peptides

Interleukin 33 (IL-33) is a member of the IL-1 cytokine family and is constitutively expressed in smooth muscle and airway epithelial cells.  IL-33 signals through the interleukin 1 receptor-like 1 (IL-1R1) and interleukin-1 receptor accessory protein (IL1RAP) receptors to ativate NF-κB and MAPK signaling pathways.  IL-33 functions to induce type 2 cytokine production in polarized Type 2 helper T (Th2) cells.  


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  • Low endotoxin
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Caution: For research use only.

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SPECIFICATIONS

Protein/peptide name IL-33
Environmentally Preferable
Protein synonyms NP-HEV
Protein/peptide type Recombinant
Protein Function Cytokine
Species Mouse
Source E. coli
Conjugation Unconjugated
Gene ID Q8BVZ5
Sequence MSIQGTSLLT QSPASLSTYN DQSVSFVLEN GCYVINVDDS GKDQEQDQVL LRYYESPCPA SQSGDGVDGK KLMVNMSPIK DTDIWLHAND KDYSVELQRG DVSPPEQAFF VLHKKSSDFV SFECKNLPGT YIGVKDNQLA LVEEKDESCN NIMFKLSKI
Protease-free N
Animal-free N
Nuclease-free N
Carrier-free Y
Endotoxin-free N
Endotoxin level Low
Endotoxin content Endotoxin LAL (EU/µg) ≤1
Biological activity Bioactivity assay: D10S cell proliferation; ED50 ≤2 ng/ml; Bioactivity ≥5.0×10⁵ units/mg
Purity ≥90%
Grade RUO
Formulation 10 mM sodium phosphate, pH 7.5
Molecular weight 17.7 kDa
Reconstitution instructions Sterile water at 0.1 mg/ml
Storage conditions –20 °C
Shipping temperature RT
Tested applications Bioassay

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