Anti-TNFR-I Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical
109-401-308-0100
76234-808EA 834.24 CAD
76234-808
Anti-TNFR-I Rabbit Polyclonal Antibody
Antibodies
Tumor necrosis factor receptor superfamily member 1A (TNF p55 Receptor) is a receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. It contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.

This antiserum against Human TNFMore Product Information
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SPECIFICATIONS

Antigen symbol TNFR-I
Environmentally Preferable
Antibody type Primary
Clonality Polyclonal
Reactivity
Host Rabbit
Isotype
Western blot Yes
ELISA Yes
ImmunoPrecipitation Yes
Purification heated to 56°C
Storage temperature Store vial at –20 °C. Aliquot contents and freeze at –20 °C. Centrifuge product if not completely clear after standing at room temperature. Stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use.
Shipping temperature Dry Ice

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