Anti-CD46 Mouse Monoclonal Antibody (CF405S) [clone: 197-2B1]

Supplier: Biotium

BNC040931-100 BNC040931-500

75913-670EA 325.12 CAD

75913-670 75913-672

Anti-CD46 Mouse Monoclonal Antibody (CF405S) [clone: 197-2B1]

Antibodies

This antibody recognizes a protein of 52 kDa-58 kDa, identified as CD46 (also known as membrane cofactor protein, MCP). CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for… More Product Information

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