Mouse Recombinant MCSF (from E. coli)

Supplier: Peprotech

AF-315-02-2UG AF-315-02-10UG AF-315-02-50UG AF-315-02-100UG AF-315-02-250UG AF-315-02-500UG AF-315-02-1MG
10778-798EA 289.25 CAD
10778-798 10778-800 10778-802 10778-804 10778-806 10778-808 10778-810
Mouse Recombinant MCSF (from E. coli)
Proteins and Peptides

M-CSF is a potent hematopoietic factor produced by a variety of cells, including lymphocytes, monocytes, fibroblasts, endothelial cells, myoblasts and osteoblasts. It is a key regulator of cellular proliferation, differentiation, and survival for blood monocytes, tissue macrophages, and their respective progenitor cells. M-CSF has been shown to play important roles in modulating dermal thickness and fertility. M-CSF is clinically used in the treatment of infection, malignancies and atherosclerosis. It facilitates hematopoietic recovery after bone marrow transplantation. Human M-CSF is reactive in murine systems, but the murine molecule exhibits no activity on human cells. Recombinant Murine M-CSF is a 36.4 kDa homodimeric protein consisting of two 156 amino acid polypeptide subunits. Manufactured using all Animal-Free reagents.


  • Carrier free
  • Animal-free


MKEVSEHCSH MIGNGHLKVL QQLIDSQMET SCQIAFEFVD QEQLDDPVCY LKKAFFLVQD IIDETMRFKD NTPNANATER LQELSNNLNS CFTKDYEEQN KACVRTFHET PLQLLEKIKN FFNETKNLLE KDWNIFTKNC NNSFAKCSSR DVVTKP


Verified by N-terminal and Mass Spectrometry analyses (when applicable).


Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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SPECIFICATIONS

Protein/peptide name MCSF
Environmentally Preferable
Protein/peptide type Recombinant
Species Mouse
Source E. coli
Animal-free Y
Endotoxin content <0.1 ng/μg of protein (<1 EU/μg).
Biological activity Determined by its ability to stimulate the proliferation of murine M-NFS-60 cells. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
Purity Greater than 98% by SDS-PAGE gel and HPLC analyses.
Formulation Lyophilized
Storage conditions −20 °C
Shipping temperature RT

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