Anti-SECISBP2 Rabbit Polyclonal Antibody

Supplier: Proteintech
12798-1-AP-150UL
10094-274EA 709.42 CAD
10094-274
Anti-SECISBP2 Rabbit Polyclonal Antibody
Antibodies
Selenium (Se) is an essential trace element required for the biosynthesis of selenoproteins, and selenocysteine insertion sequence (SECIS) binding protein 2 (SECISBP2, or SBP2) represents a key trans-acting factor for the cotranslational insertion of selenocysteine into selenoproteins. Defects in SBP2 are a cause of abnormal thyroid hormone metabolism (ATHYHM) associated with a reduction in type II iodothyronine deiodinase activity. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormalMore Product Information
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