Anti-CHGA Mouse Monoclonal Antibody (CF647) [clone: CGA/414]

Supplier: Biotium

BNC470414-100 BNC470414-500

75909-742EA 325.12 CAD

75909-742 75909-744

Anti-CHGA Mouse Monoclonal Antibody (CF647) [clone: CGA/414]

Antibodies

Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®647 is a far-red fluorescent dye (Ex/Em 650/665 nm) with excellent brightness. It also is compatible with super-resolution imaging by STORM.

Type: Primary
Antigen: CHGA
Clonality: Monoclonal
Clone: Clone CGA/414
Conjugation: CF647
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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